Lader was one of the early names leave traditional finance to work in the crypto space.
Mary-Catherine Lader, president and chief operating officer of Uniswap Labs, has reportedly resigned after four years with the company.
According to a Bloomberg report on Tuesday, Lader will stay in an advisory role before moving on to her next venture. A spokesperson for Uniswap said the company “will continue to build on her contributions,” according to the report.
Lader was one of the early big names to leave traditional finance to work in crypto space. She joined Uniswap in 2021 from BlackRock, where she was a managing director and global head of Aladdin Sustainability, according to Bloomberg.
The Uniswap protocol, Ethereum’s largest decentralized trading platform, hasn’t named its next president. Founded by Hayden Adams in 2018, Uniswap remains one of the most important players in the crypto ecosystem.
Unlike centralized exchanges such as Coinbase, Binance and Kraken, Uniswap lets users swap tokens directly with one another. Over the past 30 days, Uniswap’s trading volume crossed $73 billion, according to data from DefiLlama.
Personal news: after four incredible years as President & COO of @Uniswap, I’m starting something new.
This is a new chapter for crypto. We’ve come a long way since I started digital assets at BlackRock in 2015, and building with @haydenzadams was an awesome adventure.
I’m…
— Mary-Catherine Lader (@Mclader) July 15, 2025
Mary-Catherine Lader legacy at Uniswap
As COO and president of Uniswap, Lader oversaw the building out of internal infrastructure across finance, legal, human resources, marketing, policy and customer support, transitioning Uniswap from a developer-centric startup toward a structured organization.
In October 2022, Uniswap raised $165 million and at a valuation of about $1.66 billion.
In February, the US Securities and Exchange Commission (SEC) dropped an investigation that stemmed from a Wells Notice issued in April 2024. The case was closed in February with no enforcement taken by the regulatory body.
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